Thymus is an organ of the lymphatic system and, thus, part of the immune system. In humans, the thymus consists of two lobes, which can be spliced or just to fit tightly to each other. The lower part of each lobe broad and narrow upper; thus, the upper pole may resemble the two-pronged fork (hence the name). The thymus is located in the upper part of the chest, just behind the sternum (upper mediastinum). Newborn thymus weighs only 10-15 grams. The growth of the body continues until the onset of puberty. At this time, at the peak of its development, the mass of the body reaches 35-50 grams. After puberty, with age, the thymus undergoes obesity, atrophy and involution. In old age he barely distinguishable from the surrounding fatty tissue of the mediastinum. In 75 years, the average weight of the thymus is only 6 grams. Reducing the size of the thymus occurring during aging of an organism is often associated with lowered immunity in the elderly. As the involution of the thymus loses not only its function but also its color.
Thymus is the body in which the maturation, differentiation and immunological “training” T-cells of the immune system. The thymus produces hormones: thymosin, timolin, thymopoietin, insulin-like growth factor-1 (IGF-1), Timothy humoral factor – they are all proteins (polypeptides). If hypofunction of the thymus decreases immunity, as it reduces the number of T-lymphocytes in the blood.
The role of thymus peptides
Optimal functioning of the human immune system is directly related to the immune cells that are produced in the thymus. Modern scientific knowledge to prove that the health of the body depends on the health of individual cells. Function cells are well, then organs and organ systems work well. In order for cells worked well, they must continuously and in sufficient quantity to supply the necessary nutrients. But this one, in accordance with the latest scientific knowledge, is not enough.
For over 30 years, as scientists, doctors discovered that, for the normal functioning of cells, among other things, necessary and peptides. Peptides are small data molecules, short chains of amino acids, the address coordinates of genes. Peptides are formed in the cells of various tissues of the body during protein metabolism. Their main function is to activate the reading of the genetic information in DNA. Thus they initiate protein synthesis in cells and regulate their proper functioning. Scientists have found that deficiency of peptides in the body resulting in impaired functions in cells, cellular dysfunction, accelerated “wear” fabrics, development of pathological conditions and accelerated aging of the body. At the same time, they many studies have shown that the use of peptides and remove deficiency of peptides in the body not only contributes to the regulation of cell functions but even lost cell function can thus be restored.
For normal functions will require cells of the thymus, among other things, tissue-specific peptides (thymus peptides) that support and regulate their functions. In a small number of these peptides can be ingested with food, but the main part is formed in the cells, namely the cells of the thymus.
Cells of the thymus produce different types of proteins. Some of them are responsible for the generation of peptides that regulate the cells of the thymus. Thymus peptides are components of protein molecules tissue of the thymus. In the metabolism of proteins (the protein fraction) they are removed. One of the most important tasks of the peptides tissue of the thymus is to activate the reading of the genetic information of the DNA in the cells of the thymus. Thus peptides play a role in „key DNA“. Thymus peptides trigger protein synthesis in cells of the thymus, regulate metabolism in these cells and regulate their activity. Peptides cause the cell to function as biologically necessary. As a young healthy body. When cells of the thymus are functioning well, and the immune system works well. If the normal functions of cells of the thymus violations occurred, respectively, and the immune system works poorly. This leads to impaired function of the entire immune system. Therefore, adequate availability of thymus peptides in the body, is very important.
In the young organism peptides, as a rule, are formed in sufficient quantity and cells of the thymus work well. But with age, especially under the influence on the organism of a large number of different negative and stress factors (illness, stress, physical stress, bad and insufficient food, and so on) occurs in the body, as is known, the decrease in protein synthesis. As a result of this thymus peptides formed are also smaller. The more intense is the load, the faster is depleted in the body the level of peptides. The result of this is the lack of regulatory peptides. This leads to disruption of cell function, development of pathological conditions and accelerated wear of the main systems of the body. The more extreme conditions in which the immune system is, the higher the load on the thymus and the need for tissue-specific peptides (peptides in the thymus) and the faster arise in cells of the immune system errors and failures of their functions, if this requirement is not covered properly. This, in turn, can lead to the loss of some important functions of cells of the immune system and accelerated wear or aging of the immune system.
In such situations it is useful specifically poddergivat cells of the immune tissue (cells of the thymus). One of the most effective methods for this is the use of thymus peptides of animal origin. In all mammals, the peptides are the same. In numerous studies, scientists have shown that if you take the peptides selected from the tissues of the thymus of animals, for example from calves or pigs, and enter them into the body of another animal or person, they are accepted by the body as its own substance. Peptides have tissue-specific function. Ie, they apply only in the tissue from which they were originally allocated. Through the use of thymus peptides in the body is enriched pool of regulatory peptides produced by cells of the thymus. Thus, the use of thymus peptides helps to normalize and maintain a physiologically normal levels of peptides in tissue cells of the thymus. This, in turn, leads to normalization of metabolism in the cells of the immune system and normalize their functions to physiologically normal levels. Normalization of cell function leads to normalization of the functions of the thymus and function of the entire immune system, and thus to restore the body’s defenses.
Peptides of the thymus – clinical studies
Clinical trials have shown that thymus peptides contribute to the normalization of indicators of cellular immunity, stimulate tissue regeneration processes in the case of depression. Clinical trials have also shown the feasibility of application of thymus peptides with curative purpose in combination with any symptomatic and pathogenetic therapy used for the correction of secondary immunodeficiency States (immunomodulators, adaptogens, vitamins and other). Thymus peptides are recommended to speed up the recovery of the function of the immune system after infectious diseases, radiation and chemotherapy, the effects on the body of various extreme factors (including ionizing and microwave radiation). Also recommended for the elderly to maintain the functions of the immune system. The use of thymus peptides do not cause any side effects, complications or contraindications.
Peptides of the thymus – recommended applications
- immunodeficiency (primary and secondary)
- prevention of cancer
- in the complex immune reconstitution after diseases of different genesis
- various chronic intoxication
- the period of rehabilitation after a heart attack and stroke
- after surgery
- pathological condition leading to dysfunction of the immune system
- the impact of extreme environmental factors
- to support the immune system during aging
- as part of comprehensive programs for rejuvenation
Areas of application on the basis of the biological effects of the active substances in the product on the basis of scientific data and practical experience.
Peptides of the thymus in the preparations
Based on peptides derived from the thymus of young, healthy animals, are produced as a medication in the form of injectable solutions, tablets or capsules and biologically active food supplements.
Thymus peptides can contain up to 100 amino acids. But the active portion of the peptide is very small and usually contains up to 4 amino acids, all other regulatory action is not significant. When selecting products with thymus peptides is necessary to pay attention to the fact that they use the most short peptides. They have less inactive parts and are thus more excellent permeability and regulatory properties. We use only the peptides obtained by the method of the latest patented technology, with a molecular mass of 10 kDa. Preparations on the basis of these peptides have the best values currently in the regulation, and, therefore, also called bioregulators. It is on the basis of such peptides made our products.
Peptides derived from the thymus tissue of healthy, young animals are used in our biologically active food supplements Immunget® or Livprotect®.
Biologically active food supplements on the basis of peptides isolated from thymus is extremely safe to use. Because peptides are endogenous substances (produced in the body) and the cell cannot take more peptides than that given to her by nature, the use of peptides may not result whether to overdose whether to cause any side effects. It should be understood that the peptides have a very soft action which develops only with adequate enrichment (peptide level) of certain peptides in the body. For many years, the peptides had more than 15 million people. In all that time none of this man have not observed any contraindications or other side effects.